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Montezuma's revenge. Tourista. Tut's tummy. They are all euphemisms for a prevalent ailment that travelers may face.

Every year, in between 20 and 50 percent of international travelers-an estimated ten million Americans-create travelers' diarrhea (TD). Onset typically happens during the first week of travel, but can occur at any time throughout the trip-even following returning house. Higher-threat destinations are the establishing countries of Latin America, Africa, the Middle East and Asia. Men and women at especially higher threat for developing complications related with TD consist of young adults, immunosuppressed people, men and women with inflammatory bowel illness or diabetes, and folks taking H-2 blockers or antacids.

TD is most frequently induced by E coli and other bacteria. Most diarrhea-causing bacteria are spread by way of the water and food provide. Luckily, becoming cautious about what you eat and drink can aid decrease your danger of establishing TD, the most prevalent cause that travelers cut their vacations brief.

For travelers in higher-risk places, a single remedy alternative is a nonsystemic, gastrointestinal (GI) selective antibiotic known as Xifaxan (rifaximin) tablets 200 mg. These tablets have been approved by the FDA for therapy of individuals >12 years old with TD caused by noninvasive strains of E coli. Xifaxan has been utilised for more than 19 years in other countries with more than 500 million tablets prescribed worldwide.

"Treating travelers' diarrhea can make the distinction of feeling greater in a day, versus missing out on a few days of your trip," mentioned Bradley Connor, M.D., immediate past president, International Society for Travel Medicine.

Just before traveling, get in touch with your doctor or go to a travel clinic. In addition to taking a prescription for Xifaxan with you whilst traveling, travelers can reduce their threat for TD by practicing a couple of preventative measures.

"While TD is usually only disruptive to a holiday, there is evidence to recommend that some afflicted with TD may possibly create a far more severe situation recognized as post-infectious irritable bowel syndrome," added Connor. "It really is greatest to program ahead, take a few precautions and think about well being problems just before you travel."

If you find oneself stricken with diarrhea, drink lots of clear liquids to replace lost fluids and electrolytes.

Note to Editors: Critical Safety Information-XIFAXAN (rifaximin) tablets are indicated for the therapy of patients (>12 years of age) with travelers' diarrhea caused by noninvasive strains of Escherichia coli. XIFAXAN really should not be employed in patients with diarrhea complex by fever or blood in the stool or diarrhea due to pathogens other than Escherichia coli. XIFAXAN should be discontinued if diarrhea signs and symptoms get worse or persist a lot more than 24-48 hours and option antibiotic therapy really should be regarded as.

In clinical trials, XIFAXAN was usually properly tolerated. The most frequent side effects (vs. placebo) were flatulence: 11.3% (vs. 19.7%), headache: 9.7% (vs. 9.two%), abdominal discomfort: 7.two% (vs. 10.1%) and rectal tenesmus: 7.2% (vs. 8.8%). open in a new browser

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